What are you trying to do? I took some fluorescent images of neurons labeling two proteins. One is red and the other is in green. I exported them from SlideBook as a 16 bit tiff file then I converted the image to RGB but all of the channels are the same intensity. I am trying to view the file as it was originally rendered; with different intensities for each color and keep their respective locations on the image (my whole paper is to see the relative position of these proteins). Any ideas how to separate them? Can you just view/edit the tiff without converting it to RGB? Or if it asks when importing, try CMYK. If you want PM me the pic, and I can try and see what's happening in photoshop, but it'll be a few hours before I can do it--reinstalling my OS.